Brain injuries no match for sPIF treatment
Researchers at Yale School of Medicine and their colleagues have uncovered a new pathway to help treat perinatal brain injuries. This research could also lead to treatments for traumatic brain injuries...
View ArticleLaying siege to beta-amyloid, the key protein in Alzheimer's disease
This is the first time that a method allows scientists to monitor aggregation while simultaneously detect a structural pattern responsible for the toxicity of beta-amyloid aggregation.The researchers...
View ArticleTranscriptomics identifies genes and signaling pathways that may regulate...
Neuronal death is a normal feature of brain development but also a defining feature of neurodegenerative diseases when improperly regulated. Results of a detailed and comprehensive analysis of...
View ArticleFinding points to possible mechanism underpinning Alzheimer's and Parkinson's...
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time discovered a killing mechanism that could underpin a range of the most intractable neurodegenerative...
View ArticleNew strategy for defeating neuroblastoma found
Researchers at Karolinska Institutet in Sweden have found a promising strategy for defeating neuroblastoma – a malignant form of cancer in children – that focuses on the so-called MYCN protein. A...
View ArticleStudy expands concerns about anesthesia's impact on the brain
As pediatric specialists become increasingly aware that surgical anesthesia may have lasting effects on the developing brains of young children, new research suggests the threat may also apply to adult...
View ArticleJammed molecular motors may play a role in the development of ALS
Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to...
View ArticleFighting Alzheimer's disease with protein origami
Alzheimer's disease is a progressive degenerative brain disease most commonly characterized by memory deficits. Loss of memory function, in particular, is known to be caused by neuronal damage arising...
View ArticleFor a healthy brain, don't let the trash pile up
Recycling is not only good for the environment, it's good for the brain. A study using rat cells indicates that quickly clearing out defective proteins in the brain may prevent loss of brain cells.
View ArticleScientists to study novel mechanisms of epileptic seizures to identify...
Ten percent of Americans experience a seizure in their lifetime, with three million diagnosed with epilepsy, a chronic neurological disorder. Anticonvulsant medications can mitigate the hyperactivity...
View ArticleNecrostatin-1 counteracts aluminum's neurotoxic effects
Investigators have linked aluminum accumulation in the brain as a possible contributing factor to neurodegenerative disorders such as Alzheimer's disease. A new study published in Restorative Neurology...
View ArticleStudy suggests iron is at core of Alzheimer's disease
Alzheimer's disease has proven to be a difficult enemy to defeat. After all, aging is the No. 1 risk factor for the disorder, and there's no stopping that.
View ArticleNew study shows how ICU ventilation may trigger mental decline
At least 30 percent of patients in intensive care units (ICUs) suffer some form of mental dysfunction as reflected in anxiety, depression, and especially delirium. In mechanically-ventilated ICU...
View ArticleAnimal study reveals sex-specific patterns of recovery from newborn brain injury
Physicians have long known that oxygen deprivation to the brain around the time of birth causes worse damage in boys than girls. Now a study by researchers from the Johns Hopkins Children's Center...
View ArticleNeurons, brain cancer cells require the same little-known protein for...
Researchers at the UNC School of Medicine have discovered that the protein PARC/CUL9 helps neurons and brain cancer cells override the biochemical mechanisms that lead to cell death in most other...
View ArticleIn alcohol abusers, fish oil may reduce risk of neurodegeneration and ensuing...
Omega-3 fish oil might help protect against alcohol-related neurodamage and the risk of eventual dementia, according to a study published in the journal PLOS ONE.
View ArticleHow Alzheimer's peptides shut down cellular powerhouses
The failing in the work of nerve cells: An international team of researchers led by Prof. Dr. Chris Meisinger from the Institute of Biochemistry and Molecular Biology of the University of Freiburg has...
View ArticleCompound protects brain cells after traumatic brain injury
A new class of compounds has now been shown to protect brain cells from the type of damage caused by blast-mediated traumatic brain injury (TBI). Mice that were treated with these compounds 24-36 hours...
View ArticleNovel culture system replicates course of Alzheimer's disease, confirms...
An innovative laboratory culture system has succeeded, for the first time, in reproducing the full course of events underlying the development of Alzheimer's disease. Using the system they developed,...
View ArticleReadying the neural network
Synapse, the name for the signal-receiving site on a neuron, comes from the Greek word for contact. Neuroscientists used to maintain that neurons form one-to-one relationship to contact one another....
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